February 4, 2009

Anyone know if the Jo-1 antibody is common in fibromyalgia?

I had a positive ANA(1:320), speckled pattern. RA, lupus, Sjogrens, MCTD, and scleroderma were all negative. I did come up positive for the Jo-1 antibody though, which is usually found in polymyositis. My rheumatologist said that my muscle strength was not typical of a person that has this disorder, so I was diagnosed with fibromyalgia. With all the info I acquired on this antibody, I did not find anything that linked it with fibro. I am a little concerned of its presence since it is usually found in virtually all cases of people that have interstitial lung disease. Any feedback out there?? Appreciate it.

I haven't heard of this before with fibro - you might want to try the scientific journal databases. I would recommend searching with High Wire or PubMed (links below), although I did a quick search and couldn't find anything with the search terms ("Jo-1 antibody" AND fibromyalgia) on PubMed…

Did come across three articles on High Wire (3rd link below), including one very interesting one about ANA and fibro (will be posting that to my Yahoo group and their wiki!)

Good luck.

Filed under Polymyositis by John

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Comments on Anyone know if the Jo-1 antibody is common in fibromyalgia? »

April 17, 2006

damstr8 @ 9:07 am

Okay, your lack of muscle strength can be due to Polymyositis. "Weakness of muscles is the most common symptom of polymyositis." http://www.medicinenet.com/polymyositis/page2.htm

"Polymyositis is an inflammatory disorder of skeletal muscle that causes muscle weakness." http://www.ninds.nih.gov/disorders/polymyositis/polymyositis.htm

I can't find any link to Fibro either. I really think your problem is Polymyositis.

Good luck!
References :

biochemza @ 2:43 pm

I haven't heard of this before with fibro - you might want to try the scientific journal databases. I would recommend searching with High Wire or PubMed (links below), although I did a quick search and couldn't find anything with the search terms ("Jo-1 antibody" AND fibromyalgia) on PubMed…